Toxicology
Toxicity Clearances 

A toxicity clearance is a toxicological evaluation of materials prior to their introduction into the Army supply system. When a program identifies a technically feasible material, the manager is responsible for requesting a toxicity clearance for use of that material within their program.

Army Regulation 40-5 promulgates the toxicity clearance process in the Army.  Army Regulation 70-1 Army Acquisition Policy tasks the Toxicity Evaluation Program (TEP) with developing the toxicity clearance, including approval/disapproval for the material for a specific use. The toxicity clearance lists safety requirements.  The Department of the Army (DA) Pamphlet 70-3 requires an approved toxicity clearance prior to use of a new material or chemical. USAPHC toxicity evaluations require the following information: 

  • final chemical formulation (handled as proprietary information if required)
  • identity and application of new material; identity of material being replaced, if applicable
  • reports from manufacturers pertaining to commercial use of the product in the marketplace and material safety data sheets (MSDSs)
  • available human and animal toxicity study and epidemiology information

A toxicity evaluation is performed and clearances are approved based on the specific product application or use condition.  


A Toxicity Clearance request should be forwarded from the requesting program manager to the USAPHC at this address.

The following format should be used:

 

DEPARTMENT OF THE ARMY

US ARMY COMMAND

SOMEWHERE, USA 55515

 

 

OFFICE SYMBOL

 

 

 

 

 

MEMORANDUM FOR COMMANDER, US ARMY PUBLIC HEALTH COMMAND (MCHB-IP-TTE), 5158 BLACKHAWK ROAD, ABERDEEN PROVING GROUND, MD 21010-5403

 

 

 

SUBJECT: Request for Toxicity Clearance for [subject chemical or product]

 

 

 

1. Request a toxicity evaluation be performed and a Toxicity Clearance be issued for [subject chemical or product], a new product being considered for use in [state application]. The new product will replace [chemical name] in this particular application.

 

 

 

2. Enclosed is the technical information on the product provided by the manufacturer. The manufacturer is XYZ, Inc., Street address, City, State. The manufacturer POC is [name] at [phone number]. The POC in this office is [name] at Commercial [phone number] and DSN [phone number].

 

 

 

 

NAME

 

 

RANK

 

 

TITLE

 

 

.

For more information or to request a toxicity clearance, please contact us.