Toxicology
Wildlife Toxicity Assessments 

An integral component of a wildlife ecological risk assessment (ERA) is the development of some quantitative measure of the toxicity of a chemical to the animals of concern. This measure is often referred to as a toxicity reference value, or TRV. PHC has devised a standard method for developing toxicological profiles and toxicity reference values for military-related substances that may pose risks to wildlife. USAPHC Technical Guide 254 provides the standard practice for the development and documentation of wildlife TRVs. It is written primarily for risk assessors.  

The PHC is implementing this Standard Practice for environmental chemicals of military concern. The Standard Practice is primarily intended for use by PHC to generate wildlife TRVs that are defensible and to provide a standard set of information for practitioners in the field. If a TRV relevant to a particular Army ERA has been generated by PHC using this methodology, then its use is expected unless an alternative can be reasonably defended.

PHC is implementing this program in a phased approach, focusing upon the highest priority chemicals first. Other U.S. Army and military entities are encouraged to use this Standard Practice and our Wildlife Toxicity Assessment (WTA) reports within their ERA programs.


The following Wildlife Toxicity Assessment reports may be requested from the Health Effects Research Program at USAPHCherpinfo@amedd.army.mil.

Substance CASRN Revision No. Date Status
Acetylene 74-86-2 1 Jan 2006 Final
Aldrin 309-00-2 1 Dec 2005 Final
Amino-DNTs 35572-78-2
19406-51-0
1 (rev 2 in progress) Dec 2005 Draft
Benzo-a-pyrene 50-32-8 1 (rev 2 in progress) Dec 2005 Final
Chlordane 12789-03-6 1 Dec 2005 Final
Dinitrobenzene 99-65-0 1 Dec 2001 Final
2,4- and 2,6-Dinitrotoluene 121-14-2
606-20-2
2 May 2012 Final
Ethylene 74-85-1
 1

Jan 2006

Final
Hexachlorocyclohexane 608-73-1 2

April 2009

Updated
HMX 2691-41-0 1 (rev 2 in progress) Nov 2001

Draft

Nitrocellulose 9004-70-0

In progress

Nitrodiphenylamines 119-75-5
836-30-6
1 Apr 2006 Final
Nitroglycerin 55-63-0 2 Nov 2007 Final
Nitroguanidine 556-88-7 1 (rev 2 in progress) July 2005 Draft
Perchlorate 7790-98-9
7601-89-0
7778-74-7
1 Feb 2007 Final
PETN 78-11-5 1 (rev 2 in progress) Nov 2001 Final
Phenanthrene 85-01-8 1 Jan 2006 Final
Phenol 108-95-2 1 June 2008 Final
Picric Acid 88-89-1 1 Aug 2005 Final
Propylene 115-07-1 1 Jun 2004 Final
RDX 121-82-4 1 (rev 2 in progress) July 2002 Final
Tetryl 479-45-8 1 (rev 2 in progress) July 2002 Final
Thallium 7440-28-0 1 Dec 2007 Final
Triacetin 102-76-1 1 May 2012 Final
Trinitrobenzene 99-35-4 1 Nov 2001 Final
Trinitrotoluene (TNT) 118-96-7 1 Nov 2001 Final
Thiodiglycol 111-48-8 1  Oct 2008  Final
White phosphorus 7723-14-0 In progress    

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