Toxicology
Wildlife Toxicity Assessments 

An integral component of a wildlife ecological risk assessment (ERA) is the development of some quantitative measure of the toxicity of a chemical to the animals of concern. This measure is often referred to as a toxicity reference value, or TRV. APHC has devised a standard method for developing toxicological profiles and toxicity reference values for military-related substances that may pose risks to wildlife. USAPHC Technical Guide 254 provides the standard practice for the development and documentation of wildlife TRVs. It is written primarily for risk assessors.  

The APHC is implementing this Standard Practice for environmental chemicals of military concern. The Standard Practice is primarily intended for use by APHC to generate wildlife TRVs that are defensible and to provide a standard set of information for practitioners in the field. If a TRV relevant to a particular Army ERA has been generated by APHC using this methodology, then its use is expected unless an alternative can be reasonably defended.

APHC is implementing this program in a phased approach, focusing upon the highest-priority chemicals first. Other U.S. Army and military entities are encouraged to use this Standard Practice and our Wildlife Toxicity Assessment (WTA) reports within their ERA programs.


The following Wildlife Toxicity Assessment reports may be requested from the Health Effects Division, usarmy.apg.medcom-phc.mbx.tox-info@mail.mil .

Substance CASRN Revision No. Publication Date Status
Acetylene 74-86-2 2 2015 Final
Aldrin 309-00-2 2 2015 Final
Amino-DNTs 35572-78-2
19406-51-0
2 2015 Final
Antimony 7440-36-0 2 2015

Final

Benzo-a-Pyrene

50-32-8 2 2015 Final
Chlordane 12789-03-6 2 2015 Final
Dinitrobenzene 99-65-0 2

2015

Final
2,4-Dinitrotoluene 121-14-2 2 2015

Final

2,6-Dinitrotoluene 606-20-2 2 2015 Final
Diphenylamine 122-39-4 2 2015 Final
Ethylene 74-85-1
2

2015

Final
Hexachlorocyclohexane 608-73-1 2

2015

Final

HMX 2691-41-0 2

2015

Final

Lewisite 541-25-32 2 2015 Final
Mustard (Sulfur) 505-60-2 2 2015 Final
Mustard (Nitrogen) 51-75-2 2 2015 Final
Nitrocellulose 9004-70-0

2

2015 Final
Nitrodiphenylamines 119-75-5
836-30-6
2 2015 Final
Nitroglycerin 55-63-0 2 2015 Final
Nitroguanidine 556-88-7 2 2015 Final
Perchlorate 7790-98-9
7601-89-0
7778-74-7
2 2015 Final
Perfluorooctanoic acid 335-67-1 1 TBD Draft
Perfluorooctane  sulphonic acid 1763-23-1 1 - Draft
PETN 78-11-5 2 2015 Final
Phenanthrene 85-01-8 2 2015 Final
Phenol 108-95-2 2 2015 Final
Picric Acid 88-89-1 2 2015 Final
Propylene 115-07-1 2 2015 Final
Pyrene 129-00-00 2 2015 Final
RDX 121-82-4 2 2015 Final
Tetryl 479-45-8 2 2015 Final
Thallium 7440-28-0 2 2015 Final
Thiodiglycol 111-48-8 2 2015 Final
Triacetin 102-76-1 2 2015 Final
Trinitrobenzene 99-35-4 2 2015 Final
Trinitrotoluene (TNT) 118-96-7 2 2015 Final
White phosphorus 7723-14-0 2 2015 Final